Author(s):
Ajay I. Patel, Bhatt Isha, Amit J. Vyas, Nilesh Patel
Email(s):
pandyapritish37@gmail.com
DOI:
10.52711/2231-3915.2022.00001
Address:
Ajay I. Patel*, Bhatt Isha, Amit J. Vyas, Nilesh Patel
Pharmaceutical Quality Asuurance Department, B.K Mody Goverment Collage of Pharmacy, Near Ajidem. Rajkot.
*Corresponding Author
Published In:
Volume - 12,
Issue - 1,
Year - 2022
ABSTRACT:
In recent years, ever-increasing scientific knowledge and modern high-tech advancements in micro- and nano-scales fabrication technologies have impacted significantly on various scientific fields. A micro-level approach so-called “microfluidic technology” has rapidly evolved as a powerful tool for numerous applications with special reference to bioengineering and biomedical engineering research. Therefore, a transformative effect has been felt, for instance, in biological sample handling, analyte sensing cell-based assay, tissue engineering, molecular diagnostics, and drug screening, etc. Besides such huge multi-functional potentialities, microfluidic technology also offers the opportunity to mimic different organs to address the complexity of animal-based testing models effectively. The combination of fluid physics along with three-dimensional (3-D) cell compartmentalization has sustained popularity as organ-on-a-chip. In this context, simple humanoid model systems which are important for a wide range of research fields rely on the development of a microfluidic system. Development of microfluidic-based technology bridges the gap between in vitro and in vivo models offering new approaches to research in medicine, biology, and pharmacology, among others.
Cite this article:
Ajay I. Patel, Bhatt Isha, Amit J. Vyas, Nilesh Patel. Organ-on-a-chip and 3D printing as preclinical models for medical research and practice. International Journal of Technology. 2022; 12(1):1-8. doi: 10.52711/2231-3915.2022.00001
Cite(Electronic):
Ajay I. Patel, Bhatt Isha, Amit J. Vyas, Nilesh Patel. Organ-on-a-chip and 3D printing as preclinical models for medical research and practice. International Journal of Technology. 2022; 12(1):1-8. doi: 10.52711/2231-3915.2022.00001 Available on: https://www.ijtonline.com/AbstractView.aspx?PID=2022-12-1-1
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